Windows 10 will allow the Network adapter to be turned off to save power, which may cause Network Disconnect. 

Here is a video link showing you how to shut it off https://www.youtube.com/watch?v=ArBYUVcYUJ

Also here are screen shots walking you through the process:

Search Device Manager, open the device manager. 

Open Network Adapters

Right Click on whatever one you have, make sure you update or that it is currently up to date

Once it is up to date, right click again and open properties and open power management tab. 

Then un-check "Allow the computer to turn off this device to save power"

Another thing to look at is you could have a

 incorrect setting on the Group Policy object mapping the Manex drive uses for each user. Instead of having the setup as “update” you have to set it to “Replace”.

Apparently this setting causes the mapped network drive to be replaced every time the users computer communicates back to the Group Policy server. This then breaks any open network links for files and exe’s running from a network share. The dropout is so quick that users would not even notice but it is enough that some database programs do have problems.